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U.S. biosphere´s latest report on somatostatin
Topic Started: Friday Jan 10 2014, 09:19 AM (26 Views)
cusabiozdy

Somatostatin(SS) is a neurohormone broad action, its main role is inhibition of pituitary growth hormone (GH) secretion basis, it is also similarly inhibited stimulation by a variety of pituitary GH secretion reactions which include sport, eating, stress, low blood sugar. In addition, somatostatin can inhibit LH, FSH, TSH, PRL and ACTH secretion. Somatostatin and pituitary growth hormone cell membrane receptor binding, it plays a role for reducing intracellular cAMP and Ca2. viukhgu8rb
Somatostatin is widely distributed in the body. In the nervous system, somatostatin widespread in the central and peripheral nervous system, the brain hypothalamic somatostatin in the median eminence to the highest concentration. In the dorsal root and trigeminal ganglion neurons, there are also a significant number of somatostatin immunoreactive substances. Somatostatin widely present in the gastrointestinal tract mucosa "D" cells, which in the intestine content is low. "D" cells have long cytoplasmic processes in the pyloric gland area beyond the G cells and the "chromaffin cells" in the oxyntic gland area beyond the walls of cells and other epithelial cells.
Somatostatin paracrine mechanism consists of projections released into G cells and the wall membrane, inhibiting the secretion of gastrin and HCI in the pancreas, somatostatin from the islet "D" cells through the blood circulation effect on pancreatic and gastrointestinal role as a paracrine regulation of islet function. t4 elisa kit
Somatostatin ELISA Kit uses a double antibody sandwich ABC-ELISA method. With somatostatin monoclonal antibody coated on the microtiter plate, standards and samples of somatostatin monoclonal antibody combined with adding biotinylated somatostatin, the formation of immune complexes connected to the board, horseradish peroxidase labeled Streptavidin and biotin, the substrate working VIS blue, and finally add sulfuric acid stop solution, the OD value measured at 450nm, somatostatin concentration and the OD value is proportional to the standard curve obtained by plotting the concentration of somatostatin specimens.
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