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Fountain of youth, Close
Topic Started: Oct 2 2009, 02:34 AM (35 Views)
Sayf Udeen Ismaeel
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Icon by meagan_chelsea @ LJ
S6K1 extends life of mice, scientists say

THE fountain of youth may exist after all, after scientists claimed to have discovered means to extend the lifespan of mice and primates.

The key to eternal - or at least prolonged - youth lay in genetic manipulation that mimics the health benefits of reducing calorie intake, suggesting that aging and age-related diseases could be treated.

Scientists from the Institute of Healthy Ageing at University College London extended the lifespan of mice by up to a fifth and reduced the number of age-related diseases affecting the animals after they genetically manipulated them to block production of the S6 Kinase 1 (S6K1) protein.

Scientists have shown since the 1930s that reducing the calorie intake by 30 per cent for rats, mice and - in a more recent finding - primates can extend their lifespan by 40 per cent and have health benefits.

By blocking S6K1, which is involved in the body's response to changes in food intake, similar benefits were obtained without reducing food intake, according to the study published in the US journal Science.

The results corroborated those of other recent studies.

"Blocking the action of the S6K1 protein helps prevent a number of age-related conditions in female mice,'' explained the study's lead author, UCL professor Dominic Withers.

"The mice lived longer and were leaner, more active and generally healthier than the control group.

"We added 'life to their years' as well as 'years to their lives.'''

The genetically altered female mice lived 20 per cent longer - living a total of 950 days - or over 160 days more than their normal counterparts.

At age 600 days, the equivalent of middle age in humans, the altered female mice were leaner, had stronger bones, were protected from type 2 diabetes, performed better at motor tasks and demonstrated better senses and cognition, according to the study.

Their T-cells, a key component of the immune system also seemed more "youthful,'' the researchers said, which points to a slowing of the declining immunity that usually accompanies aging.

Male mice showed little difference in lifespan although they also demonstrated some of the health benefits, including less resistance to insulin and healthier T-cells. Researchers said reasons for the differences between the two sexes were unclear.

Recent studies by Russian scientists suggested that metformin can extend mice's lifespan.

Another drug, rapamycin, was also found to extend the lifespan of mice, according to a study published in the British journal Nature.

http://www.news.com.au/story/0,27574,26155053-23109,00.html
 
Temerit
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Immortality only 20 years away says scientist

Scientist Ray Kurzweil claims humans could become immortal in as little as 20 years' time through nanotechnology and an increased understanding of how the body works.

By Amy Willis
Published: 11:23AM BST 22 Sep 2009

Ray Kurzweil claims we could all be cyborgs in 20 years.

The 61-year-old American, who has predicted new technologies arriving before, says our understanding of genes and computer technology is accelerating at an incredible rate.

He says theoretically, at the rate our understanding is increasing, nanotechnologies capable of replacing many of our vital organs could be available in 20 years time.

Mr Kurzweil adds that although his claims may seem far-fetched, artificial pancreases and neural implants are already available.

Mr Kurzweil calls his theory the Law of Accelerating Returns. Writing in The Sun, Mr Kurzweil said: "I and many other scientists now believe that in around 20 years we will have the means to reprogramme our bodies' stone-age software so we can halt, then reverse, ageing. Then nanotechnology will let us live for ever.

"Ultimately, nanobots will replace blood cells and do their work thousands of times more effectively.

"Within 25 years we will be able to do an Olympic sprint for 15 minutes without taking a breath, or go scuba-diving for four hours without oxygen.

"Heart-attack victims – who haven't taken advantage of widely available bionic hearts – will calmly drive to the doctors for a minor operation as their blood bots keep them alive.

"Nanotechnology will extend our mental capacities to such an extent we will be able to write books within minutes.

"If we want to go into virtual-reality mode, nanobots will shut down brain signals and take us wherever we want to go. Virtual sex will become commonplace. And in our daily lives, hologram like figures will pop in our brain to explain what is happening.

"So we can look forward to a world where humans become cyborgs, with artificial limbs and organs."

http://www.telegraph.co.uk/science/scien...ntist.html
Edited by Temerit, Oct 2 2009, 04:51 AM.
 
Sayf Udeen Ismaeel
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Icon by meagan_chelsea @ LJ
Sounds like 1999 sydrome to me.
 
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